A public notice has been published by Ministry of Health and Family Welfare regarding the update to the SUGAM portal. Clinical Research Organisations (CROs) can now register online using the SUGAM portal (www.cdscoonline.gov.in). This project followed the Ministry of Health and Family Welfare’s announcement, G.S.R. 581(E), dated September 19, 2024, which enforced CRO Registration on SUGAM Portal beginning April 1, 2025.

Mandatory registration is an important step towards simplifying and regulating clinical research operations in India. The online gateway is now fully functional, allowing CROs to submit their registration applications digitally.

· Applications may only be filed through the SUGAM portal (www.cdscoonline.gov.in).

· CROs must submit applications with a checklist of materials available on the SUGAM portal.

· The portal offers simple registration options for both new and current users.

· To generate a deposit slip for Bharat Kosh, users should select “CRO Registration” or “CRO Renewal” as the payment reason on the payment page. This ensures that fees are accurately processed.

A public notice issued emphasising the importance of this online registration method in improving openness and efficiency in clinical research regulation. He asked all CROs to familiarise themselves with the portal and complete their registration well before the April 1, 2025 deadline.

The Ministry of Health and Family Welfare is dedicated to maintaining the highest levels of safety and ethical conduct in clinical research. This digital project is designed to make operations more efficient and strengthened the regulatory framework for CROs in India.